Synergistic in vitro antimalarial activity of omeprazole and quinine.
نویسندگان
چکیده
Previous studies have shown that the proton pump inhibitor omeprazole has antimalarial activity in vitro. The interactions of omeprazole with commonly used antimalarial drugs were assessed in vitro. Omeprazole and quinine combinations were synergistic; however, chloroquine and omeprazole combinations were antagonistic. Artemisinin drugs had additive antimalarial activities with omeprazole.
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ورودعنوان ژورنال:
- Antimicrobial agents and chemotherapy
دوره 43 5 شماره
صفحات -
تاریخ انتشار 1999